Cerebral metabolic rate of oxygen, intracranial tension and blood flow equivalent during isoflurane or sevoflurane anaesthesia in brain surgery
Assiut Medical Journal. 2004; 28 (1): 99-116
in English
| IMEMR
| ID: emr-65388
ABSTRACT
This study included 28 patients of ASA physical status I-II, aged 18-55 years, subjected to craniotomies for supratentorial brain tumor. They were randomly allocated into two groups to receive either isoflurane [group I] or sevoflurane [group II] anesthesia. Cerebral venous monitoring through bulb catheterization to allow assessment of global oxygen delivery adequacy. A fiberoptic extradural sensor was inserted in extramural space to monitor the ICP. Anesthesia was induced by thiopentone/fentanyl/pepecurium/isoflurane in group I, and thiopentone/pepecurium/sevoflurane in group II. Anesthesia was maintained with 1.5 MAC [1.5%] isoflurane in group I and 1.5 MAC [3%] sevoflurane in group II in FiO2 100%. The patients were mechanically ventilated in such a rate to maintain PaCO2 between 32-35 mmHg. Mean arterial blood pressure [MAP], intracranial pressure, arterial and jugular venous blood gases, arterial and jugular venous lactate concentrations were measured and times of recovery parameters were recorded. Cerebral perfusion pressure [CPP], arterial oxygen content [CaO2], jugular venous oxygen content [VjvO2], arteriojugular venous oxygen content difference [AJVDO2], cerebral oxygen extraction ratio [OER], arteriojugular lactate difference [AJVLS], lactate oxygen index [LOI], cerebral blood flow equivalent [CBF equivalent] were calculated. Times elapsed, till recovery parameters occurred, were recorded
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Blood Flow Velocity
/
Blood Gas Analysis
/
Anesthesia Recovery Period
/
Intracranial Pressure
/
Isoflurane
/
Anesthesia, General
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Assiut Med. J.
Year:
2004
Similar
MEDLINE
...
LILACS
LIS