Evaluation of the efficacy of budesonide [Neo-rinactive] in treatment of perennial allergic rhinitis monitored by acoustic rhinometry

ABSTRACT

Treatment of perennial rhinitis with nasal corticosteroids is common practice and Budesonide is one of the most appropriate drugs in this field. The topically applied Budesonide [Neo-Rinactive] was used in the treatment of 30 patients with perennial allergic rhinitis. The patients received 400 micro g Budesonide intranasally twice daily for a period of 4 weeks. The efficacy of treatment; nasal symptoms and the local side effects were estimated through a 4 point scale 0-absent; 1-mild; 2-moderate; 3-pronounced. In all patients nasal patency before and after treatment was monitored by acoustic rhinometry. The results of our study showed significant improvement of nasal patency, reduction of nasal symptoms, especially of the nasal obstruction and rhinorrhea. Only 3 patients reported for dry nose and crust formation. Intranasal inhalations with Neo-Rinactive proved to be effective with only a few side effects and could be used in the treatment of perennial allergic rhinitis. Acoustic rhinometry is accurate and objective method for evaluation of the intranasal geometry and also for monitoring of the treatment results: