EJENTAS-Egyptian Journal of ENT and Allied Sciences. 2004; 5 (2): 165-170
in English
| IMEMR
| ID: emr-65843
ABSTRACT
Vasomotor rhinitis of pregnancy has long been identified as a problem encountered by many pregnant females, this accompanies the drastic physiologic changes that occur during pregnancy. We aimed to determine the validity and efficacy of use of a well known safe drug which can be used in pregnancy, namely micronised purified diosminhesperidin combination [Daflon[R] Servier] in the improvement of symptoms of females suffering from vasomotor rhinitis of pregnancy [VMRP] and comparing it to the use of a local nasal steroid Fluticasone propionate [Flixonase[R], GSK], and a combination of both drugs. Forty-eight pregnant females suffering from symptoms and signs of VMRP contributed in the study. Subjective grading was done using the 7 most related items from the modified sinonasal outcome test [SNOT] scale scoring system, and objective grading using the rhinoscan acoustic rhinometer [by Rhinometrics[R]]. Results showed that the Diosmin-hesperidin combination only group showed similar response to combination of Diosmin-hesperidin combination and Fluticasone propionate, and both groups gave better response than the Fluticasone propionate only group. In conclusion, Diosmin-hesperidin combination is a safe and effective treatment line in control of symptoms of VMRP, either alone or in combination with Fluticasone propionate
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Signs and Symptoms
/
Steroids
/
Pregnancy
/
Treatment Outcome
/
Diosmin
/
Hesperidin
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
Language:
English
Journal:
Egypt. J. ENT. Allied Sci.
Year:
2004
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