Standrdization of Zuroor-e-Qula. A polyherbal formulation

ABSTRACT

Zuroor-e-Qula, one of the traditional polyherbal formulations is used as anti-microbial and anti-inflammatory drug. It contains mixtures of various powdered ingredients like kathsafaid [Acacia leucophloea], tabasheer [Bambusa bambos], kafoor [Cinnamomum camphora], dana heel khurd [Elettaria cardamomum], gulnarfarsi [Punica granatum], gul-e-surkh [Rosa damascena], kabab-e-khandan [Zanthoxylum armatum]. The present study involves the pharmacognostical and phytochemical standardization of this polyherbal formulation. For microscopic, diagnostic characters like epidermis of testa, endospermic cells, characteristic long fibres and other specific features were observed in the formulation. Physicochemical characters like ash values, extractive values and loss on drying were also evaluated. The preliminary phytochemical investigation revealed the presence of tannins, fixed oils, volatile oils, phenolic compounds and flavonoids. Alcoholic, petroleum ether, chloroform and aqueous extracts of the formulation were subjected to thin layer chromatographic analysis in different solvent systems and the presence of four components with different R[f] values were observed. The fluorescence analysis was also studied. Phytochemical assay for different constituents was also done