Detremination of some phenotyping markers in peripheral blood lymphocytes in acute myloid leukemic patients

ABSTRACT

Forty three patients with acute myeloid leukemia in early stage involved in this study. Twenty nine were males and fourteen were females. The patients were subdivided according to FAB international system into three different groups. [M[1], M[2], M[3]. All patients were admitted to Baghdad Teaching Hospital during Dec. 1999- Feb.2001. Twenty two apparently healthy individuals with nearly same age of the patients, eleven male and eleven female were chosen as a control group. Study of peripheral blood lymphocytes by using monoclonal antibodies [CD marker] reveled that significant reduction in CD[3], CD[4], CD19 subset of lymphocyte, whereas CD[8], and CD[56], recorded significant increase in comparison with the control group. CD[4]/CD[8] ratio revealed significant decreases in comparison with control group