Merogony of toxoplasma gondii [apicomplexa: coccidia] and its effect on the mortality and histopathology in the house mouse musculus

ABSTRACT

The merogonic stages of Toxoplasma gondii and their effects on the mortality and histopathological changes in the orally-inoculated male house mice Mus musculus with low and high doses [LD and HD] of T. gondii sporulated oocysts were investigated. The mortality percentages in LD group were 16%, 20%, 28% and 72%; while, those in HD group was 36%, 56%, 72% and 100% in the 1st-4th week, respectively. Meanwhile, the maximum mortality percentage of the control group reached 6%. The histopathological changes induced by the parasite in different organs, such as kidney, liver, brain, spleen, heart, lungs and testes were discussed