Evaluation of C-reactive protein and other inflammatory markers on acute coronary syndromes

ABSTRACT

The aim of the study is to evaluate the role of C-reactive protein [CRP], ESR, total WBC and fibrinogen in acute myocardial infarction [AMI] and in unstable angina [UA], the two very common manifestations of acute coronary syndromes [ACS]. Subjects and The present study included 100 ACS patients with age ranging from 42-60 years [mean 53 +/- 6 years], of which 35 were presented with UA a n d 65 with AMI. The study also included 25 normal subjects, age and sex matched as controls. CRP levels were elevated in both A M I [40.8 +/- 15.4mg/l] as well as in UA [32.9 +/- 17.7mg/l] patients when compared to that of the normal c o n t rols [12.6 +/- 2.8mg/l]. But the value of fibrinogen was found to be elevated significantly only in AMI patients [381.9 +/- 32.1mg%]. Other markers such as WBC and ESR were found to be elevated in both AMI and UA patients. Elevation of CRP levels can be used as adjuncts in the diagnosis of ACS