Composition moleculaire des calculs urinaires chez l'enfant en associant methodes chimique et optique

ABSTRACT

The calculi must be analyzed to find urolithiasis etiology. This investigation will allow adopting the appropriate action to avoid the stone's recurrence. Infrared spectroscopy, the reference method in calculi analysis, is unfortunately very expensive that we can't use it in our laboratory. In this study, we determine the molecular composition of urinary calculi from children using a simple and inexpensive protocol. We used the chemical method in association with optical method using binocular lens to make it more effective. We applied this protocol in studying urinary calculi collected from forty seven children and we analyzed the results according to clinical and radiological data. Our patients were aged between 2 and 16 years. The majority of them [81%] were aged over 4 years. The vesical calcui represented 51%. The calcium oxalate calculi were dominant [61,7% of cases]. The principal majority component varied according to children's age. At age less than five the major component was calcium phosphate which represented 44% while calcium oxalate represented only 22%. However, at the age of five and over, these kinds of components represented respectively 13,5% and 71% of cases. Struvite, cystin and uric acid were predominant in 6,38% of cases. This protocol allowed us to determine the molecular composition of all studied stones. It had permitted also to identify their etiology in one third of cases and to orient it in the remaining cases