dermatite atopique: aspects physiopathologiques et traitement

ABSTRACT

Atopic dermatitis represents the cutaneous facet of atopic disease. Its prevalence is in a regular increase these last decades. The physiopathology of this dermatitis is complex and not well known, implicating genetic, immunological, biochemical and environmental factors. The onset of Atopic dermatitis can start at any age of life. But it is exceptional before the age of two months; in the same way its onset after 20 years is relatively rare. It is an extremely polymorphous affection in its clinical expression that depends on the age of the subject, which necessitates establishment of diagnostic criteria. In spite of being benignity, atopic dermatitis is a chronic disease affecting negatively the quality of life of the majority of patients. The symptomatic treatment is based on topical corticosteroids and moisturizers. However, a better knowledge about its pathogenesis allows to hope for a therapeutic approach by immunomodulators, especially for the serious cases