Combined chemoradiotherapy versus radiotherapy alone in patients with esophageal cancer
Medical Journal of Cairo University [The]. 2004; 72 (1): 75-84
in English
| IMEMR
| ID: emr-67565
ABSTRACT
This study included 61 patients with locally unresectable esophageal cancer. Thirty-one patients received radiotherapy alone [RT group], the dose of radiotherapy ranged between 60-64 Gy/6-6.5 weeks, while the remaining 30 patients received radiotherapy in a dose ranged between 45-50 Gy/4.5-5 weeks plus chemotherapy [CT-RT group]. Chemotherapy [consisting of 5-fluorouracil, leucovorin and cisplatin] was given 2-3 cycles before radiotherapy and further 2-3 cycles were given after radiotherapy. The study concluded that combined modality therapy can improve the outcome in locally unresectable esophageal carcinoma with significantly better local rate, survival, progression-free survival rates and much reduction in the incidence and timing of treatment failures
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Survival Rate
/
Treatment Outcome
/
Chemotherapy, Adjuvant
/
Drug Combinations
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Med. J. Cairo Univ.
Year:
2004
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