Endothelial apoptosis and arterial thrombosis: Expression of CD31 and CD146 in recent and old thrombotic events

ABSTRACT

This study included 76 cases of recent and arterial thrombosis and 15 age-matched controls. Endothelial-derived CD 146 positive microparticles were statistically higher among cases of old thrombosis vs. controls. They were also statistically higher among old thrombosis than recent thrombosis cases. No statistical difference was found between recent thrombosis cases and controls regarding CD146. CD31 was found to be insignificantly raised among recent and old thrombotic cases in comparison to controls. Nineteen diabetics were among the patients group, but no statistical difference was detected regarding CD31 or 146 levels in comparison to non-diabetic patients. Similarly, 8 hypertensive cases were included with no statistical difference regarding CD31 or CD146 in comparison to normotensive cases. Endothelial microparticle detection among old cases of arterial thrombosis may indicate the persistence of the danger of rethrombosis