AgNOR staining in malignant and benign effusions
Pakistan Journal of Medical Sciences. 2004; 20 (1): 29-32
in English
| IMEMR
| ID: emr-68051
ABSTRACT
To evaluate the correlation of argyrophilic nucleolar regions[AgNORs] and malignancy in benign and malignant effusions. Design:
The study group consisted of pleural and peritoneal effusion samples obtained from patients suffering from various benign or malignant diseases. The cytological smears were studied by conventional haematoxylin and eosin [H and E] and silver staining for AgNORs.Setting:
The samples were obtained from patients admitted in Mayo Hospital, Services Hospital, Gulab Devi Chest Hospital and Institute of Nuclear Medicine and Oncology [INMOL].Subjects:
One hundred cases having either pleural or peritoneal effusions were selected. Fifty of these cases were positive for malignant cells and fifty had reactive mesothelial cells in them. Main OutcomeMeasures:
Assessment of AgNOR count as a diagnostic marker of malignancy. AgNOR count was helpful in differentiating benign from malignant cells. AgNOR count in malignant cells was 10.62 t 3.36 and 3.04 t 0.64 in reactive mesothelial cells. AgNOR count is a rapid, easily reproducible method of differentiating reactive mesothelial cells and malignant cells
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pleural Effusion
/
Ascitic Fluid
/
Pleural Effusion, Malignant
/
Neoplasms
Limits:
Humans
Language:
English
Journal:
Pak. J. Med. Sci.
Year:
2004
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