Adrenocortical tumors in children: a 2 cases report
Revue Marocaine des Maladies de L'Enfant. 2004; (3): 42-45
in French
| IMEMR
| ID: emr-68243
ABSTRACT
Adrenocortical carcinoma is a very rare malignant tumour in children. It has bad prognosis and the treatment protocols are not well established. We report 2 cases of adrenocortical carcinoma in children. Case 1 A 30-month-old girl was hospitalized for clitorimegaly and pubic hair. The clinical examination found an abdominal mass with paraplegia. Abdominal ultrasonography found a heterogeneous calcified mass localised in the right suprarenal region. The diagnosis was confirmed by elevated urinary 17-ketosteroids. Complementary investigations showed pulmonary, medullar and vertebral metastasis. The treatment consisted of chemotherapy [Cisplatinum + Vepeside] with no efficacy. She died after 7 months follow up. Case 2 An 8-year-old boy was admitted for a pubic and axillary's hair, with acne and abdominal mass. The abdominal ultrasonography found a heterogeneous mass in the right suprarenal region. The diagnosis was confirmed by histology after complete resection. The patient was lost from follow-up and was seen one year later with abdominal mass associated to pulmonary and liver metastasis. He received only a palliative treatment. Comments:
The adrenocortical carcinoma is a rare tumour in children [0.2% of solid tumours]. The malignant criteria and treatment protocols are not well established. The 5-year OS is 49%. The most important prognosis factor is total excision of the tumour
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Virilism
/
Child
/
Adrenal Cortex Neoplasms
/
Abdomen
Type of study:
Case report
Limits:
Female
/
Humans
/
Male
Language:
French
Journal:
Rev. Marocaine Mal. Enfant
Year:
2004
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