Endometrial thickness, serum estradiol and progesterone in women with bleeding during the use of levonorgestrel subdermal implants [norplant]

ABSTRACT

The aim of this study is to determine the changes in the thickness of the endometrium and to measure the serum estradiol and progesterone concentration in subdermal implant users and find out the relation of these parameters to the bleeding complaints. The study was conducted at the outpatient Family planning clinic, Ain Shams University, in the period from December 2002 to June 2003. 60 women using Levonorgestrel Subdermal implants [Norplant] for more than 1 year included in this comparative study and classified into. 30 women using levonorgestrel subdermal implants and have bleeding irregularities [Menorrhagia or Menometrorrhagia]. 30 women using levonorgestrel subdermal implants and have no bleeding complaints. The two groups were matched regarding mean age, weight, duration of Norplant, and endometrium thickness. The serum Estradiol was patients in the study group, while it was > 50 pg/ml in the control [P<0.01] [highly significant]