effect of incorporation of spirulina in high fat synthetic diets on certain serum and liver enzymes in rats

ABSTRACT

The effect of incorporation of Spirulina platensis is in high fat diets on liver and serum cholesterol levels and serum enzymes was investigated in albino rats. Rats were given high fat diet for a period of 21 days followed by the experimental diets containing algae 100mg and 250mg/rat/day for a period of 35 days. One group of rats was used as control I [fed with basal diet], the other group used as control 1 [fed with high fat diet] for a period of 56days. Basal diet was used for comparison. Upon feeding diets containing algae the activity of the hepatic enzymes like alanine amino transferase and alkaline phosphates increased. The activity was more pronounced in rats fed with high amounts of algae. There was marginal increase in the serum protein levels of rats fed with algae. Significant differences were not noticed in the serum and liver cholesterol levels