Cytotoxic effects of the Arum Palaestinum in Vitro

ABSTRACT

A hot water-soluble extract was obtained from the leaves of the Arum palaestinum and was subjected to cytotoxic bioassay in vitro against three tumor cell lines; Hep-2 [Larynx carcinoma] rhabdomyosarcoma and Hela [cervix carcinoma] using the MTT-assay technique. A moderate cytotoxicity of the hot extract against the three cell lines [IC50 14-20 [micro]g/ml]. The activity of the extract was compared with those of the reference standards, the cisplatin, the carboplatin and the oxaliplatin [IC50 0.3-38.7 [micro]g/ml]. The significance of these results is discussed