Role of fine needle aspiration cytology [FANC] in diagnosis of uni-locular ovarian cysts - a Cytohistological correlation

ABSTRACT

This study was carried out to assess the ability of fine needle aspiration cytology [FNAC] in the diagnosis of ovarian cysts by comparing the results with histological findings of tissue biopsies. This study includes 48 cases by ovarian cysts reported to Pathology department, Allama Iqbal Medical College, Lahore and Author's Lab. mainly from Jinnah Hospital, Lahore, Sir Ganga Ram Hospital, Lahore and Services Hospital, Lahore. In 28 cases, aspiration was done per-operatively while in 20 cases preoperatively. These aspirates were examined cytologically by making the appropriate smears. The same cysts removed surgically were then examined histologically and results were compared. In a total of 48 cases, on FNAC, serous, follicular, luteal, mucinous and endometriotic cysts were diagnosed in 12, 8, 7, 5 and 5 cases respectively with inconclusive aspirate in 11 cases. When histology was done on excised specimens of these ovarian cysts, serous cysts were found in 17 patients, follicular cysts in 10, luteal cysts in 12, mucinous cysts in 6 and endometriotic cysts in 3 patients. On correlating the FNAC and histopathology results, a sensitivity of 58.34% to 100% and a specificity of 60% to 100% were calculated in different types of cysts. It is concluded that FNAC of ovarian cysts is a fairly useful diagnostic technique which can further improve by more experience and ancillary techniques