Effect of elicitors on the enhancement of podophyllotoxin biosynthesis in suspension cultures of linum album
DARU-Journal of Faculty of Pharmacy Tehran University of Medical Sciences. 2005; 13 (2): 56-60
in English
| IMEMR
| ID: emr-70325
ABSTRACT
The possibility of enhancment accumulation of podophyllotoxin [PTOX] has been studied in cultures of cell suspension of Linum album Kotschy ex Boiss. [Linaceae] producing PTOX was studied. Attempts were made to manipulate the biosynthetic pathway of PTOX by some biotic [yeast extract] and abiotic [Ag[+], Pb[2+] and Cd[2+]] elicitors for 24 or 48 hr in Murashige and Skoog [MS] medium. Silver significantly enhanced PTOX production up to 0.24% [mg/g cell dry wt.] in cultures. This effect could be attributed to the inhibitory role of silver on production of ethylene
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Podophyllotoxin
/
Silver
/
Linaceae
Language:
English
Journal:
J. Fac. Pharm. Tehran Univ. Med. Sci.
Year:
2005
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