Effect of dried garlic powder [allium sativum] on lead content of different tissues following subclinical lead poisoning in goats

ABSTRACT

Efficacy of garlic [Allium sativum] to reduce tissue lead concentration was evaluated experimentally in goats. Eight crossbred female goats, randomly divided into two groups [A and B] were used. Goats of groups A and B received lead acetate orally at the dose of 80 mg/kg body weight, daily for 5 days. At the end of the period, goats of group B received dried garlic powder at the dose of 45 g/day/animal, orally for 5 days. Goats of group A served as lead exposed untreated controls. Comparison between mean lead concentrations of serum, urine and different tissues [bone, lung, heart, liver, kidney and skeletal muscle] of group A and B at the end of experiment showed respectively 69.6, 32.35,46.7, 34.2,27, 24.8, 9.6 and 46.6 percent reduction in group B [P<0.05]. Use of garlic dry powder following subclinical lead poisoning in goats was found to reduce tissue lead concentration considerably indicating the potential therapeutic activity of garlic against lead toxicity in goats