Synthesis of some new-isoxazolines, isoxazoles and-cyclohexen-ones derived from naphthalene of anticipated pesticidal activity

ABSTRACT

Naphthalenes are known for their widespread biological activity. Also, the pesticidal and antiviral properties have been reported for some cyclohexenone, isoxazoline and isoxazole derivatives. Such a broad spectrum of biological activities prompted us to synthesise some new isoxazolines, isoxazoles and cyclohexenones bearing the naphthalene moiety for biological evaluation. Thus, it is found in the present investigation that when hydroxyl-amine hydrochloride is allowed to react with 3-aryl-l-[2'-naphthyl]-2-propen-1-ones la-d in boiling pyridine; the oximes 2a-d are obtained, respectively, in good yield