2,4-bis [substituted] -5nitropyrimidines of expected diuretic action
Egyptian Journal of Chemistry. 1986; 29 (2): 247-51
in English
| IMEMR
| ID: emr-7136
ABSTRACT
Interest in pyrimidine diuretics have been intensified, since the discovery of the diuretic action of xanthines. A large series of pyrimidine derivatives was prepared, and its diuretic activity has been established. Also, several sulphonamides and disulphonamides are potent carbonic anhydrase inhibitors and effective diuretic agents. Therefore, this work describes the synthesis of new 2,4-bis [substituted]-5-nitro-pyrimidine derivatives, some of them include the sulphonamide moiety, which are expected to possess biological activity as diuretic agents
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Chemistry, Pharmaceutical
/
Diuretics
Language:
English
Journal:
Egypt. J. Chem.
Year:
1986
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