Studies on the anti-inflammatory and analgesic effects of extracts from marine sponges
Journal of the Egyptian Society of Pharmacology and Experimental Therapeutics [The]. 2005; 26 (1): 125-141
in English
| IMEMR
| ID: emr-72271
ABSTRACT
Two specimens of sponges collected from Red Sea, Egypt, were investigated for their contents of secondary metabolites. The crude extracts of the sponges were tested for their anti-inflammatory and analgesic effects. The toxic effects of the extracts of the two marine sponges were studied. LD50 determination revealed that the investigated extracts of Iregnella and Ircinia sps were 4.69 and 134.7 mg/100g b.wt. respectively, when injected of intraperitoneally in mice. The toxic signs were recorded within the first 24 hrs after injection. Also the two marine sponges extracts showed significant anti-inflammatory and analgesic effects
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Rats
/
Tissue Extracts
/
Anti-Inflammatory Agents, Non-Steroidal
/
Indian Ocean
/
Marine Biology
/
Marine Toxins
Limits:
Animals
Language:
English
Journal:
J. Egypt. Soc. Pharmacol. Exp. Ther.
Year:
2005
Similar
MEDLINE
...
LILACS
LIS