Proliferative changes of epidermal cells in lesions of cutaneous leishamaniasis
Journal of the Egyptian Society of Parasitology. 2005; 35 (3): 761-772
in English
| IMEMR
| ID: emr-72367
ABSTRACT
In 35 parasitologically proven zoonotic cutaneous leishmaniasis patients, the histopathological and immunohistochemical picture were studied. The haematoxylin and eosin stain, the monoclonal antibodies for T and B lymphocytes, peroxidase anti-peroxidase for P53 protein, and Feulgen staining for DNA imaging cytometry to DNA contents and S-phase [DNA synthesis of cycling cells were evaluated. The out-come results revealed that P53 and S-phase fraction and DNA content must be in mind when dealing with a human cutaneous leishmaniasis. Consequently, the early detection of any nuclear mutation and cellular proliferation in the skin leishmaniasis lesion[s] must be taken into consideration to avoid the miserable formation of the skin cancer
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Skin
/
Immunohistochemistry
/
B-Lymphocytes
/
T-Lymphocytes
Type of study:
Screening study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
J. Egypt. Soc. Parasitol.
Year:
2005
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