Frequency of thrombophilia in patients with adverse pregnancy outcome
JPMA-Journal of Pakistan Medical Association. 2005; 55 (6): 245-247
in English
| IMEMR
| ID: emr-72689
ABSTRACT
To determine the association between adverse pregnancy outcomes and thrombophilia. This is a descriptive study, incorporating retrospective analysis of patients with recurrent pregnancy losses, intrauterine deaths, abruptio placenta and early onset pre eclampsia. Patients with adverse pregnancy outcomes in whom co-morbid factors were excluded underwent screening for both acquired and inherited thrombophilia. A total of 40 patients were screened for acquired and inherited thrombophilia with adverse pregnancy outcomes. Anticardiolipin antibodies were found positive in 55% of patients and 45% of patients were found deficient for natural anticoagulants protein C and S. Two patients were found positive for both acquired and inherited thrombophilia. Thrombophilia, both acquired and inherited are associated with adverse pregnancy outcomes. Patients in whom other co-morbid factors are excluded, should be offered screening for thrombophilia. Liaison between hematologist and obstetrician is the corner stone for success
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pre-Eclampsia
/
Pregnancy Outcome
/
Abortion, Habitual
/
Antibodies, Anticardiolipin
/
Protein S Deficiency
/
Protein C Deficiency
/
Abruptio Placentae
/
Fetal Death
Limits:
Female
/
Humans
Language:
English
Journal:
J. Pak. Med. Assoc.
Year:
2005
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