Vitamin C concentration of Aqueous humor in senile cataract
JRMS-Journal of Research in Medical Sciences. 2005; 10 (5): 269-273
in English
| IMEMR
| ID: emr-72868
ABSTRACT
Oxidative agents like ultraviolet are one of the important cause of cataract and vitamin C is an important water soluble antioxidant agent in the aqueous humor. This study aimed to evaluate the concentration of vitamin C in the aqueous and plasma of patients with senile cataract. In a descriptive cross- sectional study on 85 patients [41 men and 44 women] admitted for cataract surgery, aqueous [0.2 ml] and blood [5ml] were sampled just before operation under general anesthesia from anterior chamber and vein, respectively. Spectrophotometer measured the concentration of vitamin C in both samples. The mean age was 64.3 +/- 11.1 years. Aqueous and plasma concentration of vitamin C was 4.29 +/- 1.11 mg/dl and 0.77 +/- 0.0332 mg/dl, respectively. The differences were statistical significant [P almost equal to 0]. Vitamin C of aqueous were equal in both sexes, but vitamin C of plasma in women were higher than men [P= 0.043]. The concentration of vitamin C showed no relation to the type of cataract. Vitamin C of aqueous and plasma in senile cataract are lower than normal. More study is recommended for evaluating preventive effect of high vitamin C diets or supplements
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Aqueous Humor
/
Ascorbic Acid
/
Cross-Sectional Studies
Type of study:
Prevalence study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
J. Res. Med. Sci.
Year:
2005
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