Use of antibiotics in low-risk caesarean sections; Is it wise?

ABSTRACT

A prospective double-blind, placebo controlled study, was performed to determine the effectiveness of single-dose antibiotic prophylaxis versus no antibiotics in low-risk patients undergoing caesarean section. One hundred women, at low-risk for postoperative infectious morbidity, who were to undergo caesarean section at Prince Zeid Military Hospital, were randomly assigned to receive either one gram of ceftizoxime after clamping of the cord, or no antibiotic. The incidence of febrile morbidity, endometritis and wound infection was similar in both groups. In low-risk patients, no benefit was encountered after using single-dose prophylactic antibiotic compared to no prophylaxis