Report on nine cases of malignant hyperthermia [hyperpyrexia] with reference to verapamil [isoptine] use in the treatment

ABSTRACT

Nine cases of malignant hyperthermia occured at King Hussein Medical Centre [KHMC] between 1971 and 1983. There were 78% male and 22% female patients.The incidence among young children was high in our series 44%. Overall mortality rate within two weeks of the episode was 44%. This is a review of our experience and of the literature. Malignant hyperthermia [MH] is a rare condition in which genetically susceptible subjects exhibit an abnormal response to stress and anesthesia. The first report in Jordan was 1972[1]. The objective of this paper is to review our experience at KHMC with special reference to the role of verapamil Ca ++ channel blocker in [MH] management