Testing bromocriptine dose necessary for suppression of lactation in rats: morphological study

ABSTRACT

The lowest dose of bromocriptine, necessary for suppression of lactation in rats, was estimated in this investigation. Fifty healthy lactating rats were treated with different doses of bromocriptine. Cessation of lactation was assessed clinically and histologically. Revealed that the lowest dose capable of lactation suppression is 4 mg bromocriptine / kg body wt. / day. It is very important to know the exact dose, which can suppress lactation in rats because these laboratory animals are commonly employed in experiments concerning this topic