Hyper IgE syndrome

ABSTRACT

Hyper immunoglobulin E syndrome is a rare disease. We report a case of a 2, 1/2 years old girl of consanguineous parents who presented with recurrent staphylococcal infections, failure to thrive and death of four siblings with similar illness. CBC revealed a peripheral eosinophilia and serum IgE level was markedly, raised which led to the diagnosis of hyper IgE syndrome