Ocular manifestation of tuberculosis
Bina Journal of Ophthalmology. 2006; 11 (4): 425-431
in Persian
| IMEMR
| ID: emr-76258
ABSTRACT
To determine the prevalence of ocular involvement in patients with tuberculosis [TB] infection. All patients with a new diagnosis of TB who were referred to Zahedan Tuberculosis Center underwent a complete ophthalmic examination. Any cases of known ophthalmic disease or previous ocular involvement were excluded from the study. Prevalence of ocular involvement with 95% confidence interval [95% CI] was calculated. Out of 444 eyes of 222 TB patients, 19 eyes [4.3%, 95% CI 2.6-6.6%] of 17 patients [7.7%, 95% CI 4.5-12.0%] had some ophthalmic lesions ascribable to TB. The most frequent ophthalmic lesions were choroidal tubercles in 4 eyes [21.1%]; interstitial keratitis and acute iritis each in 3 eyes [15.8%]; chorioretinitis, peripapillary nodule and lid lupus vulgaris each in 2 eyes [10.5%]; and retinal vasculitis, vitritis and lateral rectus paresis each in one eye [5.3%]. The ocular involvement was unilateral in 88.2%. Multiple logistic regression analysis revealed that only the duration of TB before treatment had direct correlation with ocular involvement [odds ratio= 5.22, 95% CI 1.57-17.35]. The frequency of ocular involvement in TB in the study population is at least 3 times greater than other countries. Early treatment of TB can reduce ocular involvement and prevent other complications of the disease
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Choroid Diseases
/
Iritis
/
Chorioretinitis
/
Retinal Vasculitis
/
Eye
/
Keratitis
Limits:
Humans
Language:
Persian
Journal:
Bina J. Ophthalmol.
Year:
2006
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