Outcomes of Phacoemulsification in Eyes with and without Pseudoexfoliation

ABSTRACT

To evaluate the incidence of pseudoexfoliation syndrome [XFS] in patients with senile cataract who were scheduled for phacoemulsification and intraocular lens implantation [PE + IOL] and to compare the outcomes of PE+IOL between eyes with and without XFS. We retrospectively reviewed 2200 eyes with cataract undergoing PE + IOL. All procedures were performed by a single surgeon [M.A.J] at a private clinic. Patients with XFS were considered as the case group and age and sex matched patients without XFS were selected as controls. The incidence of XFS was 4.1% [90 eyes]. Mean age was 71.8 +/- 7.1 and 70.7 +/- 6.7 years in the case and control groups, respectively. XFS was unilateral in 60% of the cases. The prevalence of hypertension, diabetes mellitus [DM] and diabetic retinopathy [DR] was 31.1%, 6.7% and 0% in the XFS group vs 42.9%, 26.6% and 5.2% in the control group, respectively [P< 0.05]. Glaucoma was present in 25.6% of the XFS group and 6.5% of the control group [P<0.0001]. Vitreous loss occurred in one eye in each group; only one eye had zonular dehiscence in the XFS group. Iris stretching was performed during surgery in 11.1% in the XFS group and 1.9% in the control group [P<0.0001]. Anterior capsule contraction occurred in 9.1% of the XFS group vs 0% in the control group [P=0.007]. PE + IOL in patients with XFS is as safe and effective as pure senile cataract. The incidence of DM and DR is significantly lower in XFS