Seroprevalence of Varicella Zoster Virus in Children from Shiraz-Iran
IJI-Iranian Journal of Immunology. 2006; 3 (1): 43-46
in English
| IMEMR
| ID: emr-76755
ABSTRACT
Varicella-zoster virus [VZV] causes herpes zoster and varicella [Chicken-pox], usually a mild disease which is diagnosed clinically with few complications. However, in neonates and healthy adults it can have a severe presentation. Herpes zoster results from VZV reactivation later in life. To determine the seroprevalence of VZV in elementary school children aged 6-10 years in Shiraz, Iran. A cross-sectional seroprevalence survey was conducted on 270 healthy subjects. All serum samples were investigated for immunoglobulin G [IgG] antibody against VZV using a commercial enzyme linked immunosorbent assay [ELISA]. Among the studied population, 175 [64.8%] had no detectable antibody levels. The overall seroprevalence rate was 35.2%. A breakdown of seropositivity to VZV according to age was as follows; 10 years old, 50%, 9 years old, 48.2%, 8 years old, 27.3%, 7 years old, 32.1%, and 6 years old, 13.2%. As VZV susceptibility in the studied age groups was higher than the expected rate, therefore childhood VZV vaccination is recommended in our region
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Enzyme-Linked Immunosorbent Assay
/
Epidemiologic Studies
/
Prevalence
/
Cross-Sectional Studies
Type of study:
Prevalence study
Limits:
Humans
Language:
English
Journal:
Iran. J. Immunol.
Year:
2006
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