Folic acid treatment of hyperhomocysteinemia in dialysis patients

ABSTRACT

We examined the effect of Folic Acid [FA] administration on the homocysteine level of chronic hemodialysis patients. The study group included 16 patients [11 male and 5 female] with CRF; their ages ranged from 20 to 57 years, who were undergoing dialysis at the dialysis unit of Zaid Bin AI-Hussein Hospital in Jordan [2004/2005]. [Hcy] level, of patients' group after supplementation with [FA] led to a significant decrease in homocysteine level [39.7%], [p<0.001], while no significant difference in homocysteine level was shown in control patients. Supplementation of the diet with [FA], at levels above the current recommended dietary allowances, reduces elevated homocysteine levels in [CRF] patients