[Study of serum IgE and nasal secretion eosinophils count in patients with allergic rhinitis]

ABSTRACT

Allergic rhinitis is a chronic disease of upper respiratory tract which can be presented as asthma. Some investigators have reported a significant relationship between the disease and the number of eosinophils in nasal secretion of the patients. This study aims to evaluate the serum IgE and it's relation with nasal secretion eosinophils count in patients with allergic rhinitis. In this study, serum IgE of 92 patients with non anatomical nasal complication were investigated using ELISA method [IEMA WELL Q-D]. Nasal secretion smears of the patients were also evaluated for eosinophils count. Age, sex, profession and past history of allergic reactions in patients and their families were also investigated. 48. 9% of the patients had high titers of serum IgE [>100 IU/ml]. Also, eosinophils over 5/HPF were seen in 15. 6% of patients, nasal secretion smears. There was no significant relationship between eosinophils count and presence of allergic rhinitis in the patients. Otherwise, there was a significant correlation between rhinitis and patients, profession and their locality of living [P<0. 05]. Detection of serum IgE is mandatory for diagnosis of allergic rhinitis. Besides, it seems that nasal secretion eosinophils count alone is not a reliable finding for diagnosis of the disease