Intrapartum fetal monitor and fetal outcome in cases of pregnancy induced hypertension treated with labetalol pindolol, with clopamide and alphmethyldopa

ABSTRACT

Twenty-four women with pregnancy induced hypertension [PIH] presenting to Al-Azhar University Hospital in the last trimester of pregnancy were divided into three equal groups. Each group received therapeutic doses of a hypotensive drug [labetalol, pindolol with clopamide and alpha methyldopa]. The effect of these drugs was studied during the intrapartumperiodandthe results were compared with eight normosensitive patients during labor [control group]. No significant change in fetal heart rate [FHR] could be attributed to the drug administrated in case of labetalol alpha methyldopa.As regards pindolol with clopamide, a significant change in long term variability was observed in patients suffering from sever PIH. The pHof fetal blood samples taken from the umbilical cord [UC] did not correlate with maternal pH in patients who received pindolol with clopamide