Histopathological and histochemical studies on experimentally infected hamsters with pygidiopsis genata

ABSTRACT

Haematoxylin eosin stained sections showed the stunted growth of the villi as well as widening of the intervillous spaces in the regions where the worms were seen lodged. A focal cellular reaction was seen in the lamina propria. The enzymatic activity was markedly reduced in the villi in succinic dehydrogenase, nonspecific esterase and alkaline phosphatase; where as marked reduction in the activity of acid phosphatase was noticed particularly in the glands. Those changes suggest a disturbance in both digestive and absorptive mechanisms