Trial of I/V amiodarone in paroxysmal atrial fibrillation

ABSTRACT

Amiodarone in I/V form can be a very useful tool for the control of tachyarrhythmia, in doses of 20 mg/kg/body wt. about 1/3 -1/4 of which may be given as bolus, and the rest continued as infusion till either the arrhythmia is aborted, or a good control achieved, following which a maintenance oral does may me given if required. Pre-treatment with enzyme inducers may be helpful in bringing about arrhythmic control earlier than Amiodarone alone. The number of patients in this series was however very small and further studies are required to confirm these results. However, the conversion of 14/15 from atrial fibrillation to sinus rythm is very encouraging