Common pitfalls in the conduct of clinical research
Medical Principles and Practice. 2006; 15 (1): 1-8
in English
| IMEMR
| ID: emr-79502
ABSTRACT
Recently, paradigm shift from expert opinion towards evidence-based medicine has occurred encouraging physicians to base their treatment decisions on the best available research evidence. In the hierarchy of evidence randomized clinical trials [level 1 evidence] are considered of the highest quality [least biased] while non-randomized studies represent lower levels [levels 2-4]. Several pitfalls in the design and conduct of clinical research include lack of randomization, lack of concealment, lack of blinding, and errors in hypothesis testing [type I and II errors]. A basic understanding of these principles of research will empower both investigators and readers when applying the results of research to clinical practice
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Research Design
/
Evidence-Based Medicine
Type of study:
Controlled clinical trial
/
Practice guideline
Limits:
Humans
Language:
English
Journal:
Med. Princ. Pract.
Year:
2006
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