Rosia-Dorfman disease presenting as bilateral eyelid swellings
Medical Principles and Practice. 2006; 15 (2): 163-165
in English
| IMEMR
| ID: emr-79533
ABSTRACT
To report a case of sinus histiocytosis with massive lymphadenopathy [Rosai-Dorfman disease] in an extranodal site with unusual presentation. A 19-year-old girl presented with bilateral upper eyelid swellings of 2 years duration due to tumor. The masses were excised and sent for histopathological examination. Microscopic examination revealed similar features in both masses in the form of a collection of large histiocytic cells showing emperipolesis [lymphocytophagocytosis]. The histiocytic cells stained positively with S-100 protein and CD68. The background comprised small lymphocytes and plasma cells. Based on the overall features a diagnosis of sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman disease was made. The present case highlights one of the forms in which extranodal Rosai-Dorfman disease can manifest itself. It is important to keep this differential diagnosis in mind whenever such histopathological features are encountered
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Syndrome
/
Histiocytosis, Sinus
/
Eyelid Diseases
/
Lymphatic Diseases
Type of study:
Case report
Limits:
Female
/
Humans
Language:
English
Journal:
Med. Princ. Pract.
Year:
2006
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