Apgar score of neonate; comparison of thiopentone and propofol during c-section

ABSTRACT

A comparative study was conducted in CMH, Malir, CMH, Kharian and WT [Pvt] Ltd. Gynaecology and Obstetrics, Multan from April 2001 to March 2004. The Apgar score of neonate was compared for thiopentone or propofol in C-section patients. Two groups of patients were made. Group-A was induced with thiopentone and group-B was induced with propofol. Each group had 100 patients. In group-A 13 neonates required manipulation and 2 neonates in group-B also required manipulation like mask ventilation or endotracheal intubation and one of drugs like atropine to improve apgar score. 13% neonates in group-A and 1% neonates in group-B required manipulation. This clearly shows the superiority of propofol over thiopentone as an induction agent in C-section. The P value of group-A was 0.13 and for group B was 0.02 and had had a statistically significant difference