[Factors influencing homocysteineamia in type 2 diapetic patients]
Tunisie Medicale [La]. 2006; 84 (5): 279-281
in French
| IMEMR
| ID: emr-81457
ABSTRACT
Previous studies have suggested that hyperhomocysteinaemia [Hcy] could be a strong and independent cardiovascular risk factor. Many factors could influence the serum concentration of Hcy such as vitamin B 12, folic acid, renal failure, hypothyroId status, ovarian failure and cancers. So the aim of our study was to evaluate the prevalence of hyperhomocysteinaemia among 54 type 2 diabetic patients and to study, its relationship with vitamin B 12, folic acid and Metformin. Were excluded all patients with an evident cause of hyperhomocysteinaemia. Mean age of patients was 52.8 years. Mean Hcy was 11,7 + 6,9 micro mol/l. The prevalence of hyperhomocysteinaemia was 27,8% in our group. There were eight [14%] patients with vitamin B 12 deficiency and three among them had hyperhomocysteinaemia There was no folic acid deficiency and no relationship with Metformin treatment. We suggest a wide screening of hyperhomocysteinaemia in type 2 diabetic patients and folic acid or vitamin B 12 supplements if necessary
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Vitamin B 12
/
Cardiovascular System
/
Prospective Studies
/
Diabetes Mellitus, Type 2
/
Folic Acid
/
Metformin
Limits:
Female
/
Humans
/
Male
Language:
French
Journal:
Tunisie Med.
Year:
2006
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