Immunological study on cigarette smokers Part I effect of smoking on the serum immunoglobulin levels

ABSTRACT

Twenty asymptomatic apparently healthy adult male smokers, 20 to 60 of age, ranging from mild to heavy smokers were compared with 10 apparently healthy non-smokers of the same sex and age range as regards serum immunoglobulin levels. The results obtained revealed a significant increase, in serum IgE level in smokers compared to non-smokers irrespective of the extent of smoking. Serum IgG and IgM levels declined with smoking and this decline was statistically significant in heavy smokers for IgG and in moderate and heavy smokers as well as in smokers in general for IgM. Serum IgA ana IgD levels showed no significant changes