Biological evaluation and study of polysaccharides of Dalbergia sissoo Roxb growing in Egypt
Egyptian Journal of Pharmaceutical Sciences. 2007; 48: 39-52
in English
| IMEMR
| ID: emr-82359
ABSTRACT
The extracts of Dalbergia sissoo Roxb growing in Egypt, the polysaccharides prepared from leaves, stem and bark and the major constituent in the plant [biochanin A] were subjected to screening of anti-inflammatory, anti-pyretic and analgesic activities adopting new methodology. The anti-tumor, anti-oxidant, and antimicrobial activities of these substances were also examined. Since the polysaccharides prepared from different organs [leaves 2.5%, stem 2.2%, bark 1.2%] possessed anti-inflammatory activities, they were subjected to further phytochemical studies, using paper chromato-graphy and GC/MS analysis. The polysaccharides were heterogeneous in nature and lacked uronic acids. The use of GC/MS to study the monomeric composition of polysaccharides in the acid hydrolysate indicated that the leaf polysaccharides consist mainly of rhamnose [77%] in addition to glucose [23%]. The stem polysaccharide consists of rhamnose [47%], glycerol [46%] and galactose [7%]. The bark polysaccharide consists of rhamnose [18%], fructose [2.5%], glucose [74.5%] and galactose [6%]
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Polysaccharides
/
Plant Extracts
/
Anti-Inflammatory Agents
/
Anti-Bacterial Agents
/
Antioxidants
Language:
English
Journal:
Egypt. J. Pharm. Sci.
Year:
2007
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