Comparing antioxidant capacity and vitamin C values between umbilical cord and maternal blood plasma and those in newborns with hypoxia

ABSTRACT

Oxygen intoxication plays an important role in the pathogenesis of some fetal diseases such as encephalopathy, ischemia and hypoxia. Antioxidants can reduce oxidative damage in newborns. The object of this research was measuring total value of antioxidant and vitamin C in blood sample of pregnant women before delivery, and also in umbilical cord blood of their newborn, and repeating these measurements 48 hours after birth in newborns with hypoxia and controlling group. The sample included 32 healthy pregnant women presented for delivery and also their newborns. The total values of antioxidant and vitamin C in plasma were measured by staining methods. There was no statistical meaningful difference in total values of antioxidants and vitamin C in women's blood and their newborn's cord blood. Also total values of antioxidant and vitamin C meaningfully increased in newborns with hypoxia after 48 hours. total values of antioxidant and vitamin C in blood plasma of newborn, increases in oxidative damage as a defense mechanism