Traumatic brain injury in pediatric age group; Predictors of outcome in pediatric intensive care unit

ABSTRACT

To determine predictors for outcomes of traumatic brain injury [TBI] in infants and children younger than twelve years admitted to our pediatric intensive care units [PICU]. This is a retrospective cohort study from 2004-5, done at the PICU of King Fahad Hofuf Hospital, Eastern Province, Saudi Arabia. One hundred and six patients with TBI; 65 boys and 41 girls ages 12 or under, with a mean age of 5.7 years, were included. Of them, 11.3% died [Deaths group], 11% survived with neurological deficits [NDgroup], and 77% survived with no neurological deficits [NND-group]. The potential predictors for death or neurological deficits were examined. 83% of deaths had initial Glascow coma scale [GCS] of brain CT was abnormal in 92% of deaths and ND groups, but in only 37% of NND. Combined brain pathologies were found in 92% of deaths, 63% of ND and only in 5% of NND. Hypotension was seen in 67% of deaths, 17% ND and only in 1% of NND. Mechanical ventilation was required in all deaths and more than half of ND. Liver enzymes were high in 50% of deaths and 66% of ND but in only 20% of NND. Serum albumin was low in 33% of deaths, 42% of ND and only 1% NND. Glasgow coma score, brain CT findings, combined brain pathologies, hypotension, high liver enzymes and low serum albumin predict outcome after TBI in pediatric age group