Association of dyslipidemia with acute and myocardial infarction

ABSTRACT

Ischaemic heart disease is a leading cause of death throughout the world. CAD has been recognized among all age groups especially above forty years of age more frequently in recent years. To determine the dyslipidaemia and waist hip ratio as a risk factor of Myocardial Infarction [MI]. This descriptive comparative type of study was conducted in the medical Ward, Nishtar Hospital, Multan during the period from January 2006 to January 2007. A total of 150 patients of first acute myocardial infarction age ranges from 35 years-70 years were included in the study. Among these patients 74% were males and 26% females. Two modifiable or controllable risk factors including dyslipidaemia. [Truncal obesity] were studied in this study. Patients were diagnosed on he bases of typical history of chest pain, ECG changes, raised cardiac enzymes or troponin T positive. Fasting lipid profile was done. Dyslipidaemia i.e. high total cholesterol, low density lipoproiein cholesterol and low HDL-cholesterol was statistically significant in all patients of ML 74% patients have dyslipidaemia including high total cholesterol, high LDL-C and low HDL-C. Triglyceride level was not found statistically significant. Incidence of IHD showed linear relation with age i.e. risk increased with the age only 14% patient belonged to age group 35-30 year as compared to 34%i patient who belong to age group more than >50 years. Mostly females were post-menopausal. It was also found that upto 80% had two or more than two risk factors. In conclusion, dyslipidaemia and Truncal obesity are important modifiable risk factors. These risk factors must he sought out in all high risk groups and where possible be treated for both primary as well as secondary prevention of CAD