Study of toxicity and haemagglutinating activitiy of a purified intracellular toxin and extracellular crude toxin isolated from pseudomonas aeruginosa
Medical Journal of Islamic World Academy of Sciences. 2007; 16 (4): 171-179
in English
| IMEMR
| ID: emr-84256
ABSTRACT
The action of purified intracellular toxin [PIT] from Pseudomonas aeruginosa was examined in brine shrimp lethality bioassay. The LC50 of the PIT was calculated to be 25 microg/ml. The PIT agglutinated both albino rat and rabbit erythrocytes more potently than did extracellular crude toxin [ECT]. Galactose and Dmannose, however inhibited the agglutination property of PIT and ECT respectively. Intradermal injection of PIT caused changes on the tissues of rabbit skin at a lower dose than that of ECT
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Artemia
/
Rabbits
/
Rats
/
Hemagglutination Inhibition Tests
/
Erythrocytes
/
Galactose
/
Hemagglutination
/
Mannose
Limits:
Animals
Language:
English
Journal:
Med. J. Islamic World Acad. Sci.
Year:
2007
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