Assessment of correlation of 4 hour and 24 hour urine protein in pregnant women with hypertensive disorders

ABSTRACT

This study was designed to determine the presence of any correlation between 4-hour and 24-hour urine protein values in pregnant women with hypertensive disorders in Besat Hospital, in Sanandaj in 1383. This was a cross-sectional study and included 58 inpatient pregnant women who had been initially diagnosed as having hypertensive disorders in pregnancy. Urine samples were collected in 2 successive periods. The first 4 hour and the next 20-hour urine samples were collected in separate containers. The urine volume, urine protein and creatinine concentration of the 4-hour and 24-hour samples were separately measured and the correlation between both urine samples was determined by Pearson's Correlation Method. A total of 58 patients were entered into this study, 42 of them with no proteinuria and 16 with mild proteinuria. The value for the 4-hour urine protein was found to correlate with those of the 24-hour samples [R=0.821] in patients with hypertensive disorders in pregnancy. Also sensitivity and specifity of 4-hour urine test were 70.6% and 90.2% respectively. Total protein values of 4-hour urine samples correlated well with those of 24-hour urine samples [p<0.001] of the patients with hypertensive disorders in pregnancy