Comparative evaluation of intravenous propofol, thiopentone sodium and ketamine for short surgical procedures

ABSTRACT

The increasing popularity of outpatient surgery has prompted the search for new anaesthetic agent that can provide safe and effective anaesthesia with a rapid and smooth recovery We compared three induction agents, namely propofol, thiopentone sodium and ketamine to find the most suitable agent for this purpose. This prospective study was conducted at HIMS, Dehradun on 90 ASA I, II patients of either sex and in age group 16-65 years undergoing minor surgical procedures under general anaesthesia not requiring endotracheal intubation. The patients were randomly allocated into three groups of 30 patients to receive either inj propofol 2-2.5 mg/kg 1V [Group A], inj thiopentone 3-5 mg/kg IV [Group B], or inj ketamine 1-2 mg/kg IV [Group C]. It was noted that the induction time was shortest with Inj thiopentone and recovery was quickest with Propofol. Heart rate, SBP, DBP decreased with injection thiopentone and Propoiil being more in case of injection Propofol in comparison to injection to thiopentone. Inj Ketamine led to increase in all the parameters. Propofol is an ideal choice for short surgical procedures