Effect of cuminum extract on the motility of isolated rabbit jejunum

ABSTRACT

This study was carried out to evaluate the effects of decoction of Syrian cuminum seeds [13 W/V] was evaluated on the isolated rabbit's jejunum. 2 ml of the extract was added to the [100mL] nutrient solution of the jejunum. Two parameters were used to evaluate the effect of cuminum extract the frequency and width of the intestinal motility within 5 mints on the strip. Cuminum extract showed a significant inhibition on the width of the motility of isolated rabbit's jejunum [P< 0.05]. However this extract had no significant effect of the frequency of the motility. Cuminum cyminum water extract can inhibit the motility of rabbit's jejunum that support the traditional use of this plant as antispasmodic herb in the Syrian traditional medicine